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System of Record Vs. System of Reference: 5 Key Differences

By Gaine Technology

System of Record Vs. System of Reference: 5 Key Differences
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Today’s healthcare and life sciences fields rely heavily on precise and reliable data to drive advancements in quality care, research, and innovation. Understanding the differences between system of record vs. system of reference is key to this end, enabling effective data management emphasizing both the source for data creation and maintenance, and a centralized source for cleansed and consolidated data.

Given the vast volumes of complex data created and managed by healthcare organizations—higher than any other industry—leveraging systems of record and systems of reference is also necessary to maintain data integrity, privacy, security, and compliance across the many data sources in a company’s ecosystem.

This guide will clearly define the system of record and system of reference, outline the important differences between the two, and explain how they can complement each other to optimize data management.

Key Takeaways:
  • Systems of record provide the authoritative source for original data, while systems of reference consolidate and harmonize data for analytical use.
  • Overcoming integration challenges, such as interoperability and data privacy, is key to leveraging the full potential of both systems for operational efficiency and strategic decision-making.
  • Master data management solutions are crucial for integrating systems of record and systems of reference, ensuring data consistency and quality.
  • Strategic implementation of systems of record and systems of reference enhance both day-to-day operational processes and high-level, data-driven strategies.


What Is a System of Record?

A system of record (SoR) is the primary source for data within an organization, where original records are first created and subsequently maintained. It is the definitive source for a specific dataset—for any piece of data it holds, the SoR is where that data was originally entered into the system and is kept up-to-date.

This makes SoRs crucial for operational processes that rely on the most current data, such as transaction processing. Key characteristics of a system of record include:

  • Authoritative Source: It’s the official repository for a specific type of data within an organization.
  • Data Originality: Data within an SoR is original, entered directly at the source of the transaction or interaction.
  • Auditability: Changes to data within an SoR can be tracked, providing a clear audit trail for compliance and verification purposes.
  • Integrity and Reliability: Ensures the data’s accuracy, consistency, and reliability, serving as the foundation for operational processes.

In the healthcare and life sciences sectors, systems of record are crucial for managing patient records, laboratory results, pharmaceutical inventories, and clinical trial data.

For example: Electronic health record (EHR) systems act as systems of record for patient medical histories, diagnoses, and treatment plans, ensuring healthcare providers have accurate and up-to-date information for making informed care decisions.

Laboratory information management systems (LIMS) serve as SoRs for storing and managing detailed laboratory test results, critical for research, diagnosis, and regulatory compliance.

What Is a System of Reference?

A system of reference (SoRf) is a consolidated platform that aggregates, harmonizes, and presents data from multiple systems of record. It serves as a central repository for accessing the most accurate, current, and complete version of data from across the organization.

Key features of a system of reference include:

  • Data Consolidation: Aggregates data from various SoRs and data sources into a single repository.
  • Data Harmonization: Cleanses, matches, and merges data to ensure accuracy and eliminate duplicates.
  • Current and Complete Data: Maintains the most up-to-date and comprehensive view of data available.
  • Accessibility: Provides a centralized access point for data users across the organization.

In healthcare and life sciences, systems of reference are commonly used for patient data management, research data analysis, and regulatory reporting. For instance, a SoRf might integrate patient data from different EHR systems, laboratory information systems, and billing systems to create a comprehensive patient profile that can be accessed by healthcare providers for a holistic view of patient health.

Similarly, in research settings, a SoRf could consolidate experimental data, clinical trial results, and publication data from various sources, enabling researchers to analyze data more effectively and derive meaningful insights.


5 Key Differences Between System of Record vs. System of Reference

Understanding the nuanced differences between system of record vs. system of reference is crucial for effective healthcare data management. While both play integral roles in the data ecosystem, their functions, purposes, and impacts on organizational processes vary significantly. Let’s dive deeper into 5 of the foundational differences between the two:

1. Source of Data Creation vs. Source of Data Consolidation

The system of record is where data is initially created and captured, marking the genesis of a data record within an organization. This is typically seen in operational activities. For example, when a patient’s medical details are entered into an EHR system during registration, that system becomes the SoR for that patient’s data.

A system of reference, on the other hand, specializes in aggregating and harmonizing data from multiple SoRs. It does not create original data, but rather refines and consolidates it to provide a comprehensive and unified view, which is essential for data analytics and reporting purposes.

2. Operational Processes vs. Decision Support

Systems of record are foundational to the daily operational processes of an organization. They ensure that activities such as patient care, billing, and inventory management are conducted based on accurate and current data.

Systems of reference are designed to support decision-making and strategic planning. By offering a consolidated view of data, SoRfs enable organizations to perform in-depth analyses, generate insightful reports, and make informed decisions that shape future strategies and improvements.

3. Data Maintenance and Integrity

For a system of record, maintenance emphasizes the ongoing accuracy and timeliness of the data it houses. In systems of record, data is not only created but must also be actively maintained to reflect real-time updates, changes, and deletions.

This level of maintenance is critical for operational integrity, ensuring every transaction or interaction is based on the most current data available. The rigorous upkeep of an SoR directly supports day-to-day operational activities of an organization, such as patient care, where the accuracy of a patient’s medical history or medication records can have immediate consequences.

In contrast, the system of reference plays a different role in data maintenance. While it also emphasizes data quality, its focus is on integrating and reconciling data from multiple SoRs to create a unified and accurate representation of information across the organization. A SoRf’s maintenance is geared toward ensuring that consolidated data is not only accurate but also harmonized, removing inconsistencies and duplications that may exist across different systems of record.

This process enhances the data’s reliability for analytical and reporting purposes, supporting strategic decision-making rather than operational immediacy. The SoRf ensures that stakeholders have access to a comprehensive and trustworthy dataset that reflects the best available information from across the organization’s various data sources.

4. Authoritative Source vs. Trusted Source

A system of record is recognized as the authoritative source for its specific dataset, holding the definitive version of transactional data. It is the primary reference point for operational data within its domain—for example, EHRs at a hospital, or supply chain management systems for a pharmaceutical company.

Meanwhile, a system of reference is regarded as the trusted source for high-quality and consolidated data, founded in streamlined data aggregation and harmonization processes. This makes it the preferred source for high-level data analysis and reporting across the organization.

5. Adaptability to Organizational Needs

The flexibility and scalability of systems of record and systems of reference differ in relation to adapting to organizational needs. Systems of record are built to be robust and reliable, capable of supporting a wide range of operational activities. However, their structures may offer less flexibility due to stringent data control and compliance requirements.

Systems of reference, given their role in data consolidation and analysis, often need to be more scalable and adaptable. They must efficiently integrate new data sources and manage increasing volumes of data, ensuring the organization’s analytical capabilities keep pace with its evolving needs.



Integrating Systems of Record and Systems of Reference

Integrating systems of record and systems of reference within healthcare and life sciences organizations is essential, but it demands a nuanced approach. Data teams must balance the need for accurate, real-time data with the requirement for comprehensive, analytical insights. This comes with challenges that need to be addressed both during the integration process and for ongoing data management.

For example: Ensuring interoperability between disparate systems, maintaining data privacy and security in compliance with regulations like HIPAA, and achieving scalability to handle growing data volumes are significant hurdles. Moreover, aligning integration with organizational workflows and processes requires careful planning and execution.

Master data management (MDM) tools are essential for executing a successful system of record and system of reference integration, offering structured, systematic approaches to ensure data consistency and quality across both platforms. MDM facilitates the seamless flow of information from several systems of record into the system of reference where it can be cleansed and streamlined for broader organizational use.

Even with an MDM solution in place, healthcare organizations must adopt strategic data management approaches that include thorough evaluation of existing data infrastructure, clear data governance policies, and implementing the MDM solution optimally to bridge the gaps between data creation and data consolidation. 

When done successfully, organizations can achieve the best of both worlds when it comes to data: operational efficiency rooted in accurate, real-time data, as well as insightful, data-driven strategies at the highest levels, driving strategic advancement and a competitive advantage in your market.

The Bottom Line

Understanding the differences between systems of record vs. systems of reference and integrating them effectively are foundational to modern healthcare data management. These systems, when effectively harmonized, provide a robust framework for maintaining data integrity, enhancing operational efficiency, and driving strategic decision-making.

The challenges of integration, while significant, can be navigated through the strategic implementation of master data management solutions. Gaine’s Coperer platform is a highly scalable, ecosystem-wide MDM solution that’s specifically designed for the unique challenges of the healthcare and life sciences industries.


Learn more about Coperer—start your real-time demo today.


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